The detection of primary malignant circulating prostate cells; their significance and clinical utility

by Robert Warren Hessurotoday-logo

One of the major challenges for medical science and physicians in dealing with prostate cancer is determining whether or not a specific prostate cancer is malignant – aggressive – or benign. The state of the prostate cancer makes all the difference in the choice of treatment. And it certainly matters to prostate cancer survivors.

The recent research cited in the article below shows that testing to see if circulating prostate cancer cells (CPC) are positive both for P504S and for PSA, “…in comparison with total PSA, free PSA, PSA velocity and density, proved to be superior in predicting the presence of prostate cancer at initial biopsy, and was superior to the Montreal nomogram.”

“The evidence seems to support the concept that the detection of primary malignant CPCs is associated with the presence of clinically significant prostate cancer. If used as a sequential test may decrease the number of unnecessary prostate biopsies. That their presence does not imply the presence of distant disease (micrometastasis) and such as a prognostic factor has limited value.


Prostate cancer patient takeaway

A higher than normal PSA or an unusual physical exam generally are the first indications that prostate cancer may be present. The test cited in this research is another step in finding a more reliable test for determining if a particular prostate cancer is aggressive and warrants immediate treatment.


How to catch prostate cancer early

Early detection remains the critical factor in surviving prostate cancer. The PSA blood test is a simple and inexpensive test that costs less than the annual Pap smear women take for detecting cervical cancer. [Federal Pap smear program.]

Here are three easy steps to implementing your personal prostate cancer insurance [read survival] program . . .

  1. Take an annual PSA blood test beginning at age 35. You can order the PSA test through your doctor, or you can schedule a test at a local laboratory near you for just $35.00.  Click the following WalkInLab link to find a lab in near you: WalkInLab.
  2. Once you have the results – it should be a number between 0.00 and 4.0 depending on your age* – create a free account at ProstateTracker and record your PSA number. ProstateTracker will send an email reminder when your next test is due.
  3. If your number is over 3.0 or it has increased by .75 or more from the previous year, you should talk with your doctor or medical services provider as soon as possible.


1 in 7

Remember that only one in seven men will have prostate cancer so y0ur chances are pretty low. But, if you are the one that prostate cancer touches, surviving more than five years means you must find it early when it is treatable. That simple PSA test is so quick and easy. And it brings peace of mind or early detection. Both are priceless.


Early prostate is a “Silent Killer”

Prostate cancer is often called a “silent killer” because it generally shows no symptoms until it reaches an advanced stage where treatment and cure are very difficult if not impossible.

The best thing men can do is to begin PSA testing at age 35 and personally track their PSA number, looking for any increase in value.


Read the Full Abstract Here

You can read the full abstract of the article by clicking the following link:


*PSA stands for prostate specific antigen, which is a protein released by prostate tissue. As men age, their prostates naturally grow larger, increasing the amount of PSA in the blood. While there are “guidelines” for the amount of PSA at specific age ranges, there are many exceptions. If you have a positive PSA number, you should consult with a doctor or medical services provider.